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Case 1 :05-ov-00160-KAJ-IVIPT Document 93 Filed 02/13/2006 Page 1 of 3
IN THE UNITED STATES DISTRICT COURT
FOR THE DISTRICT OF DELAWARE
NOVOZYMES A/S, )
Blaintiff, 3
v. 3 C.A. No. 05-160-KA}
GENENCOR INTERNATIONAL, INC. and T
ENZYME DEVELOPMENT )
CORPORATION, )
Defendants. T
DEFENDANTS’ SUPPLEMENTAL NOTICE REGARDING 35 U.S.C. § 282
As set forth in the Joint Pretrial Order, iiled February I, 2006, defendants
Genencor International, Inc. and Enzyme Development Corporation rely upon the following prior
art regarding the patent in suit:
I. Suzuki et al., Amino Acid Resiclues Stabilizing a Bacillus Alp/ra-/Inzylizse
Againsi irreversible T/iermoinactivcition, J. Bio}. Chem. 264: 18933-I8933 (I989).
2. Bisgaard—Erantzen et ai., PCT Publication No. WO 95/ 10603, titied
"Amylase Variants" and dated. April 20, I995.
3. Maehins Bl al., Crystal Siruczfure of Calci'iini—rieplereil Bacillus
liclzenyfirniis alphraainylase at 2.2/43 Resolution, I. Moi. Bio}. 246: 545-559 (i995).
4. Gray ei al., Structural Genes Encoding the Therinop/iilic alplm»Aiii)¤lase of
Bacillus steai·or/aerirzopliilus and Bacillus licl1eng’orin1`s, J. Bacteriol. l.66: 635—643 (1986).
5. Gray, U.S. Patent No. 5,093 ,25 7, entitled "Hybrid Prokaryotie Polypeptides
by in vivo Reeornbinationf (I992).

Case 1:05-cv—00160-KAJ—IV|PT Document 93 Filed 02/13/2006 Page 2 of 3
6. Yuuki. er ai., Complete Nne/eoticie Sequence of n Gene Coding for Hearn
cinc!—pH—Sznb/e oQo}m—Ainylase of Bnciffiis lie/zeny"ornzis.· Coinpnrison of the Amino Acid
Sequences of Three Bacteriol Liquejring ci/pho-Aniyioses Deducedjieoni the DNA Sequences, J.
Biochem. (Tokyo) 9S(5); 1147-1 156 (1985).
MORRIS, NICHOLS, ARSHT & TUNNELL LLP
Donaid E. Reid (#105 8)
OF COUNSEL: Jason A. Cincilla (#4232)
1201 North `Mnrket Street, 18th Floor
JONES DAY Wilmington, DE 19899-1347
Tharari Gregory Lanier Telephone: (302) 6589200
Kenneth R. Adamo Attorneys for Deferzdeizts
.13116 L. FTS}/(1 _ GenencorInternational, Inc. and
2882 Sand Hill RGHCL Sum? 240 Enzyme Developmeni Corporoztion
Menlo Park, CA 94025
J ONES DAY
Thomas E. Friebel
Margaret B. Brivenlou
222 East 415* Street
New York, NY 10017-6702
February 13, 2006

Case 1:05-cv—00160-KAJ—IV|PT Document 93 Filed 02/13/2006 Page 3 of 3
C.ERTIFI.CATE OF SERVICE
l, Donald E. Reid, hereby certify that on the l3m day of February, 2006, a copy of
Defendants’ Supplemental Notice Regarding 35 USC. § 282 was served by electronic tiling (e-
mail) upon the following counsel of record;
Andrew A. Lundgren, Esquire (alouda1‘e.n.@*r-goat.eorn)
Young Conaway Stargatt & Taylor LL·p
1000 West Street
Wilniingtora, DE l9SGl
Samuel S. Woodley, Esquire (;awoog§_lev‘ Robert C. Sullivan, lr., Esquire (gsellir·art{ééT2rrlztrbx*law.con;)
Darby & Darby P.C.
805 Third Avenue, 27m Floor
New York, NY 10022
David K. Tellekson, Esquire (dtel`le1<$on@2Edarb®f.i;rw.eortt.)
Darby & Darby P.C.
1191 Second Avenue
Seattle, WA 98101
{/”“~t_x1 KM U
Donald E. Reid (#1058)