Free Opening Brief in Support - District Court of Delaware - Delaware

Case 1:07-cv-00731-GMS

Document 7

Filed 11/20/2007

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Case 1:07-cv-00731-GMS

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EXHIBIT 1

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EXHIBIT 2

Case 1:07-cv-00731-GMS

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EXHIBIT 3

Case 1:07-cv-00731-GMS

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EXHIBIT 4

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EXHIBIT 5

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EXHIBIT 6

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EXHIBIT 7

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EXHIBIT 8

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EXHIBIT 9

IMPAX LABS - Press Release Case 1:07-cv-00731-GMS

Document 7-5

Filed 11/20/2007

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Press Release IMPAX Comments on Lawsuit Related to Generic Version of Opana(R) ER HAYWARD, Calif.--(BUSINESS WIRE)--Nov. 19, 2007--IMPAX Laboratories, Inc. (OTC:IPXL) today confirmed that Endo Pharmaceuticals Holdings Inc. and Penwest Pharmaceuticals Co. have filed a lawsuit against the Company in the United States District Court for the District of Delaware alleging patent infringement related to IMPAX's filing of an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) for oxymorphone hydrochloride extendedrelease tablets CII, a generic version of Opana(R) ER. IMPAX's submission includes a Paragraph IV certification stating the Company believes its product does not infringe U.S. Patent Nos. 7,276,250, 5,662,933 and 5,958,456 or that the patents are invalid or unenforceable. The suit alleges infringement of U.S. Patent Nost. 5,662,933 and 5,958,456 and also seeks declaratory judgment that the court to declare that the Paragraph IV Certification Notices that IMPAX served on Endo and Penwest are null, void and of no legal effect and that, therefore, the Court has no subject matter jurisdiction over the patent infringement claims. "We believe that our Paragraph IV certification for generic Opana ER was proper, that our product does not infringe any valid, enforceable patent, and, as such, we will vigorously defend this lawsuit. Furthermore, we believe that the rescission of our ANDA by the FDA was inappropriate and we are continuing to work with the FDA to allow our ANDA to stand," said Larry Hsu, Ph.D., president and chief executive officer of IMPAX Laboratories. Endo Pharmaceuticals Holdings Inc. and Penwest Pharmaceuticals Co. manufacture and market Opana ER for the treatment of moderate to severe pain. According to Wolters Kluwer Health, U.S. sales of Opana ER tablets were approximately $48.8 million in the 12 months ended September 30th, 2007. About IMPAX Laboratories, Inc. IMPAX Laboratories, Inc. is a technology based specialty pharmaceutical company applying its formulation expertise and drug delivery technology to the development of controlled-release and specialty generics in addition to the development of branded products. IMPAX markets its generic products through its Global Pharmaceuticals division and markets its branded products through the IMPAX Pharmaceuticals division. Additionally, where strategically appropriate, IMPAX has developed marketing partnerships to fully leverage its technology platform. IMPAX Laboratories is headquartered in Hayward, California, and has a full range of capabilities in its Hayward and Philadelphia facilities. For more information, please visit the Company's Web site at: www.impaxlabs.com. "Safe Harbor" statement under the Private Securities Litigation Reform Act of 1995: To the extent any statements made in this news release contain information that is not historical, these statements are forward-looking in nature and express the beliefs and expectations of management. Such statements are based on current expectations and involve a number of known and unknown risks and uncertainties that could cause IMPAX's future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to, possible adverse effects resulting from the delisting of and suspension of trading in IMPAX's stock, the SEC proceeding to determine whether to suspend or revoke the registration of IMPAX's securities under section 12 of the Securities Exchange Act, IMPAX's delay in filing its 2004 Form 10-K, its Form 10-Q for each of the first three quarters of 2005, 2006, and 2007, its Form 10-K for 2005 and 2006, the actual time that will be required to complete the filing of IMPAX's delinquent periodic reports, IMPAX's ability to obtain sufficient capital to fund its operations, the difficulty of predicting FDA filings and approvals, consumer acceptance and demand for new pharmaceutical products, the impact of competitive products and pricing, IMPAX's ability to successfully develop and commercialize pharmaceutical products, IMPAX's reliance on key strategic alliances, the uncertainty of patent litigation, the availability of raw materials, the regulatory environment, dependence on patent and other protection for innovative products, exposure to product liability claims, fluctuations in operating results and other risks detailed from time to time in IMPAX's filings with the Securities and Exchange Commission. Forward-looking statements speak only as to the date on which they are made, and IMPAX undertakes no obligation to update publicly or revise any forward-looking statement, regardless of whether new information becomes available, future developments occur or

http://phx.corporate-ir.net/phoenix.zhtml?c=67240&p=irol-newsArticle_print&ID=10793... 11/20/2007

IMPAX LABS - Press Release Case 1:07-cv-00731-GMS

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otherwise. CONTACT: IMPAX Laboratories, Inc. Larry Hsu, Ph.D. President & CEO 510-476-2000, Ext. 1111 Arthur Koch, CFO 215-933-0351 www.impaxlabs.com or Investor Relations Contacts: Lippert/Heilshorn & Associates, Inc. Kim Sutton Golodetz, 212-838-3777 [email protected] Bruce Voss, 310-691-7100 [email protected] www.lhai.com SOURCE: IMPAX Laboratories, Inc.

http://phx.corporate-ir.net/phoenix.zhtml?c=67240&p=irol-newsArticle_print&ID=10793... 11/20/2007

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EXHIBIT 10

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EXHIBIT 11

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